Mechanism of action
Infliximab belongs to the group of biologic medications for psoriasis (a group of anti-TNF-α drugs). The drug works to block the effects of tumor necrosis factor alpha - TNFα, alter the immune response, create a radical treatment effect on the skin.
This is a drug that is widely used in the treatment of psoriasis in dermatology hospitals. Currently, the drug is used by 2 routes: injection and oral.
Indications for use
This is a psoriasis medication for patients with moderate to severe plaque psoriasis and psoriasis.
DosageEffective medications for psoriasis
Infliximab is an injectable drug that is widely used in the treatment of psoriasis in dermatological hospitals
Usually, the dose of intravenous infusion to treat psoriasis is 5mg / kg / time, infusion for at least 2 hours. Continue infusion at week 2 and 6 after the first infusion. And then every 8 weeks, the patient will transmit 1 time.
Side effects
Very effective in treating psoriasis, but Infliximab still causes some side effects such as:
Increased risk of infection: The most common is respiratory tract infection, in addition to sepsis, new or recurrent tuberculosis, Candida infection.
Causes the risk of initiating or worsening autoimmune diseases such as scattered sclerosis, Lupus syndrome ...
Malignant diseases such as cholecystitis, lymphoma, and non-pigmented skin cancer.
Vasculitis, skin infection
Contraindicated for use
Infliximab is avoided by pregnant and lactating women
If a pregnant mother accidentally uses the drug, the infant needs to be exposed to the drug for several months after birth.
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